Premature deaths in Iran have become a bitter reality and of concern for the country’s health care system as the main cause of deaths in Iranians under the age of 70 are cardiovascular diseases, ensued by heart attack and / or brain stroke.

In obtaining the results from the Golestan Cohort Study, the study’s executive team sought a simple strategy for reducing MI and TIA rates, as well as premature deaths, while relying on data from more than 50,000 participants in the study and documented causes of deaths. In a study carried out by two English scholars, Wald and ... , a drug named "Polypill" was finally proposed for the prevention of MI and TIA.

The main phase of the study, which its implementation with 8,000 samples began in 2013, is currently in its final stages. The preliminary evaluations have demonstrated its efficacy in the primary and secondary prevention of complications in patients with a history of cardiovascular disease, as well as primary and secondary prevention in healthy individuals who are at risk for developing cardiovascular disease over the age of 50, and has not shown any significant side / adverse effects.

Currently, Polypill which is sponsored by the Barakat Foundation, has entered Iran’s Pharmacopoeia and its manufacturing license has been issued by Alborz Drug Company. This medication is available in two types of Polypill 1: aspirin (81 mg), enalapril (5 mg), atorvastatin (20 mg) and hydrochlorothiazide (12.5 mg), and Polypill 2 (for those who suffer from coughing, a side effects induced by enalapril), which includes aspirin (81 mg), valsartan (40 mg), atorvastatin (20 mg) and hydrochlorothiazide (5.12 mg).